Computational pathology bioinformatics

SBIOS

Product-grade AI for automated cell annotation, biomarker intelligence, and synthetic H&E data that helps pathology teams move from slide images to confident biological insight.

Slide SBI-2407 96.8% QC
14,282cells annotated
27biomarker regions
3.2Msynthetic patches

Built for pathology AI teams

From whole-slide images to structured, validated biological signals.

SBIOS connects image analysis, multimodal biomarkers, and generative pathology data into one workflow for research groups, diagnostic AI companies, and translational medicine programs.

Product suite

Three specialized systems, one pathology intelligence layer.

Annotated pathology slide with cell classification overlay
01

Automated cell annotation for pathology slides

Detect, classify, and spatially map cells across H&E and IHC slides with review-ready overlays.

Biomarker discovery workflow and metabolite panel
02

Biomarker discovery

Convert morphology, expression, and spatial context into candidate biomarkers for stratification and response modeling.

Synthetic H&E tissue strips
03

Synthetic H&E data

Generate representative slide patches for rare-class balancing, stain normalization, and privacy-aware expansion.

Annotation engine 96.8% confidence

Interactive cell annotation review

Click a product above to inspect how SBIOS packages slide evidence, model confidence, and downstream exports for that workflow.

Spatial precision
Review efficiency
Data readiness
Selected SBIOS product evidence

Scroll intelligence

Annotate every cell in context.

SBIOS maps cell identity, tissue boundaries, and confidence into an explorable pathology layer.

Pathology story visual
14,282 cells review-ready annotations
96.8% confidence
01

Cell annotation

Classify tumor, immune, stromal, and rare cells while preserving slide-level traceability.

02

Biomarker mapping

Turn morphology and spatial neighborhoods into candidate biomarkers and expression signatures.

03

Synthetic H&E

Generate diverse, quality-controlled patches for rare classes, stain variation, and model stress tests.

04

Validation loop

Review confidence maps, expert corrections, and exportable evidence before deployment.

Video demo

Cell typing in H&Es using AI

The original SBIOS cell-typing video is preserved here, now framed as a product demo inside the updated frontend experience.

Interactive analysis

Tune the pathology layer and watch the readout change.

Explore how SBIOS separates tumor, immune, and stromal neighborhoods, then increases synthetic H&E diversity for stronger model development.

Tumor-enriched region Dense epithelial clusters with high annotation certainty and clean spatial boundaries.
64% Balanced rare-class expansion

Workflow

Designed around scientific traceability.

Every output is tied back to slide provenance, model confidence, and spatial evidence.

Slide intake normalized Ingest captures context before computation.

SBIOS keeps slide metadata, stain information, and acquisition details attached to every tile so downstream analysis stays traceable.

Affiliated organizations

Bio-Techne Columbia University University of North Dakota University of Arizona NIH Google

Partner with SBIOS

Build pathology AI with cleaner labels, stronger signals, and richer data.

Ready to elevate your research? Let our bioinformatics expertise drive your next discovery.

Or email us directly at [email protected]